Clinical Study Details
AusTrials is conducting a research study to test the efficacy of a new investigational treatment for adults with high levels of lipoprotein(a).
Scientific evidence strongly suggests that having high levels of a substance called lipoprotein (a) [Lp(a)] can significantly increase the risk of heart and blood vessel problems like heart disease and strokes. This risk seems to be independent of other factors and is even linked to conditions like kidney disease and valve problems in the heart.
Interestingly, unlike some other factors that affect heart health, such as diet or exercise, Lp(a) levels aren’t easily influenced by lifestyle changes or medications that lower cholesterol. Even when people take medications like statins, which are meant to reduce heart risks, high Lp(a) levels can still pose a danger.
Here at AusTrials, we are studying an investigational treatment (LY3819469) which aims to reduce lipoprotein (a) and reduce the occurrence of serious heart events like heart attacks or strokes.
The investigational treatment could help improve heart health by reducing the risk of major heart problems in adults with high levels of lipoprotein (a) [Lp(a)]. This research aims to see how LY3819469 affects the occurrence of serious heart events like heart attacks or strokes in adults who either already have heart disease or are at risk for it. By studying this, we hope to gather more evidence about how LY3819469 could benefit people in this group.