Cardiovascular Disease Research Study

Clinical Study Details

AusTrials is conducting a research study to test the efficacy of a new investigational treatment for adults with high levels of lipoprotein(a).

Scientific evidence strongly suggests that having high levels of a substance called lipoprotein (a) [Lp(a)] can significantly increase the risk of heart and blood vessel problems like heart disease and strokes. This risk seems to be independent of other factors and is even linked to conditions like kidney disease and valve problems in the heart.

Interestingly, unlike some other factors that affect heart health, such as diet or exercise, Lp(a) levels aren’t easily influenced by lifestyle changes or medications that lower cholesterol. Even when people take medications like statins, which are meant to reduce heart risks, high Lp(a) levels can still pose a danger.

Here at AusTrials, we are studying an investigational treatment (LY3819469) which aims to reduce lipoprotein (a) and reduce the occurrence of serious heart events like heart attacks or strokes.

The investigational treatment could help improve heart health by reducing the risk of major heart problems in adults with high levels of lipoprotein (a) [Lp(a)]. This research aims to see how LY3819469 affects the occurrence of serious heart events like heart attacks or strokes in adults who either already have heart disease or are at risk for it. By studying this, we hope to gather more evidence about how LY3819469 could benefit people in this group.

To be eligible, participants must:
  • Be aged 18 years of age and older.
  • Have established cardiovascular disease or are at risk for a first cardiovascular event.
  • Have an Lp(a) laboratory measurement that is equal to or more than 175 nmol/L.

 

All treatments and procedures are free, and participants will be reimbursed for reasonable expenses associated with study visits.

The study is being conducted at the following locations:

  • AusTrials Sunshine – Melbourne, VIC
  • AusTrials St Leonards – Sydney, NSW

 

Please contact AusTrials on 1300 190 841 for further information or follow the link below.

Register your interest in this study here.
If you would like to learn more about participating in the study please enter your details below and we will be in touch shortly.






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