Meaningful Relief with Flurbiprofen 8.75 mg Spray in Patients with Sore Throat Due to Upper Respiratory Tract Infection

This paper presents the result from a randomised, double-blind study in adults with sore throat due to upper respiratory tract infection who took flurbiprofen (n = 249) or placebo spray (n = 256). Pain relief was assessed using the Sore Throat Relief Rating Scale.  In this study, flurbiprofen spray provided significantly greater relief versus placebo…

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Safety Profile of the Adjuvanted Recombinant Zoster Vaccine: Pooled Analysis of Two Large Randomised Phase 3 Trials

The ZOE-50 and ZOE-70 phase 3 clinical trials showed that the adjuvanted recombinant zoster vaccine (RZV) was ≥90% efficacious in preventing herpes zoster in adults. This article presents a comprehensive overview of the safety data from these studies. Adults aged ≥50 (ZOE-50) and ≥70 (ZOE-70) years were randomly vaccinated with RZV or placebo. Safety analyses…

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