Oct142022

Efficacy of the Adjuvanted Recombinant Zoster Vaccine (RZV) by Sex, Geographic Region, and Geographic Ancestry/Ethnicity: A Post-Hoc Analysis of the ZOE-50 and ZOE-70 Randomised Trials

Recent Publications

Herpes zoster (HZ) risk appears to vary by sex and geographic ancestry/ethnicity. In 2 randomised clinical trials, participants received 2 doses of adjuvanted recombinant zoster vaccine (RZV) or placebo intramuscularly, 2 months apart. In this post-hoc analysis, the efficacy of RZV against HZ and postherpetic neuralgia (PHN) were investigated by sex, geographic region, and geographic…

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Oct142022

A New Fully Liquid Presentation of MenACWY-CRM Conjugate Vaccine: Results from a Multicentre, Randomised, Controlled, Observer-Blind Study

Recent Publications

The currently licensed quadrivalent MenACWY-CRM conjugate vaccine presentation consists of two vials (lyophilised MenA and liquid MenCWY) to be reconstituted before injection. A new fully liquid formulation in a single vial has been developed to further improve the vaccine presentation. Since the MenA structure is subject to hydrolytic degradation, this study was conducted to compare…

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