Previous research has shown that the experimental drug being trialled in this study blocks the activity of a particular protein and may reduce pain. It is hoped that blocking this protein may potentially reduce knee pain in patients with OA.

The study drug is administered as 3 injections under the skin of your stomach or thigh, once a week for 16 weeks.

You will be required to come to our clinic 27 times and there will be one phone call over a period of 36 weeks (approximately 8 months).  At each visit you will see the study doctor and then the research team for study assessments.

There is no cost for the vaccine or study visits, and you will be compensated for time and travel.

Eligibility

To be eligible, participants must:

•    Be aged between 40 – 80 years old.
•    Be clinically diagnosed with Knee Osteoarthritis
•    Have symptomatic Knee Osteoarthritis for at least 6 months.
•    Be generally in good health or have well-controlled medical conditions.
•    NOT have any history or current diagnosis of any other inflammatory joint conditions

Further eligibility applies